Zillon
and its analogues were tested for antiviral activity against Raniket
disease virus and the Vaccania virus in a stationary culture of
chorioallantoic membrane ( CAM ) of chick embryo. The values of non
toxic doses to the order of 50 percent of CAM culture ( approximate
LD 50 ) and antiviral activity recorded are presented in table
below.
Antiviral activity of Zillon and its analogues against
Raniket Virus Disease.
( Trials conducted at Central Drug Research Institute of
CSIR, Lucknow, India )
*0.000032 HA
unit / cultur. ** There was no HA titre in the pressence if the
Zillon ( -X ), i,e. Resulted in full inhibition.